Cited variant interpretation

Varia reports only the fraction of your genome where peer-reviewed evidence is strong enough to stand on. The result is fewer findings, each one traceable back to a trusted, cited source, so you can understand what the science actually says, with confidence in where every finding comes from.

Every finding traced to peer-reviewed evidence

  • NEJM
  • JAMA
  • Nature
  • Cell
  • ClinVar
  • CPIC

Caffeine metabolism

Neutral
CYP1A2 rs762551
A,A

CYP1A2 fast metabolizer. Rapid caffeine clearance and efficient metabolism of CYP1A2 substrates.

1 peer-reviewed source

An example finding. Not your personal result.

Private by design

Your file is read in your browser and never uploaded, so there's no copy of your genome on our servers to leak or lose. We keep only your name, email, and whether you've paid.

Privacy policy

Made for your doctor, not your supplement cabinet

You get findings and their citations in a form you can hand to your physician at your next appointment. Varia never tells you what to take or do, so you won't find a dose or a supplement protocol anywhere on it.

Read the medical disclaimer

What Varia covers

Varia groups its curated findings into focused health areas. Every finding, in every area, traces back to cited evidence.

Heart & Lipids

Cholesterol, lipoproteins, clotting, and vascular and iron-handling variants.

Brain & Cognition

Alzheimer's risk and clearance genetics, plus cognition, mood, and behavior.

Metabolism & Longevity

Blood sugar, longevity and telomere biology, methylation and nutrients, and inflammation.

Medication Response

How your genetics affect the way you metabolize and respond to medications.

Cancer Risk

Common, low-penetrance variants from genome-wide studies. Population-level associations only, not personal risk scores or screening guidance.

Autoimmune

Common non-HLA variants linked to autoimmune conditions, with explicit limits on what consumer files can assess.

How we cover each area

How it works

  1. 1. Load your file. It is read in your browser, never uploaded.
  2. 2. See a free preview. Confirm the scan worked, no findings revealed.
  3. 3. Get your full results. Free. Yours permanently, with free re-scans.

Don't have your DNA file yet?

It's already in your testing account, a few clicks away. Most people have it in hand in about two minutes. Pick where you tested:

23andMe
  1. Sign in, open the profile menu, and go to Settings.
  2. Under 23andMe Data, open Download Raw Data and submit the request.
  3. They email a download link, usually within a few hours. Download the .zip and upload it here.
AncestryDNA
  1. Sign in, open DNA, then Settings.
  2. Click Download Raw DNA Data and confirm through the email Ancestry sends.
  3. Come back to the same page, download the .zip, and upload it here.
MyHeritage
  1. Sign in and open DNA › Manage DNA kits.
  2. On your kit's three-dot menu, click Download raw DNA data and confirm through the email.
  3. Return to the kits page, download the .zip, and upload it here.
Whole-genome sequencing (VCF)
  1. Already have a .vcf or .vcf.gz from Nebula, Dante, Sequencing.com, or similar? You're set.
  2. Upload it straight to Varia. Whole-genome files are read in your browser, the same as chip data.

Start your free scan See the full step-by-step guide

Free scan, preview, and full results.

Your scan confirms your file processed and shows how many variants we found across your domains.

Your interactive dashboard and Varia Genomic Brief are free. Your file stays on your device.

Free and private. Re-scan anytime as the database grows. See what is included.

Module explainers by health area

Plain-language explainers for each curated module, grouped by health area.

On Varia's active watchlist, monitored against the peer-reviewed literature for catalog inclusion: